Psa Density Normal Range

Alternatively psad may be calculated using mri measurements 3 of prostate volumes or less commonly using post surgical histopathological measurements of prostate volumes 4.

Psa density normal range.

Possible cut off levels depending on the tpsa should be established. For example a man 50 to 59 years of age with a psa level that is 0 5 ng ml one year and increases to 2 5 ng ml the following year may be viewed as having a normal psa level but the rate of change in his psa psa velocity would be worrisome for an underlying prostate cancer. Small amounts of psa ordinarily circulate in the blood. Divide the psa test number by the size of the prostate gland found during the transrectal ultrasound to find the psa density.

Also because psa levels vary greatly from one person to another it is hard to give one number that is normal men under 50 for men under 50 healthy psa levels will usually range between 3 and 2 5 nanograms per milliliter ng ml with an average of 1 2. The psa test measures the level of psa in a man s blood. To determine the density of psa you are going to need your psa result and the volume of your prostate or its dimensions. The psa density psad is a calculation performed at diagnosis and is the serum psa level ng ml divided by the volume of the prostate gland ml 1 prostate volume is calculated from trus measurements 2 3.

The psa test can detect high levels of psa that may indicate the presence of prostate cancer. Men with larger prostates logically have more prostate cells and in general produce more psa regardless of whether they have cancer or not. For this test a blood sample is sent to a laboratory for analysis. Prostate specific antigen or psa is a protein produced by normal as well as malignant cells of the prostate gland.

Therefore determining what a high psa score means can be complicated. Detection of any prostate cancer was significantly higher with psa density compared with psa between 4 and 10 ng ml area under the curve auc 0 70 vs 0 53 respectively. P 0001 and 10 ng. Psa is produced by prostate cells whether the cells are normal or cancerous.

Psa is mostly found in semen which also is produced in the prostate. In total 1809 men with no pretreatment of the prostate were. The objective of this study was to evaluate the prostate specific antigen psa density psad the quotient of psa and prostate volume compared with the percent free psa fpsa in different total psa tpsa ranges from 2 ng ml to 20 ng ml. The results are usually reported as nanograms of psa per milliliter ng ml of blood.

Calculating psa density can help your doctor analyze your prostate specific antigen psa score and determine whether or not your results are abnormal.